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Antipsychotics cause hyperglycemia in some older diabetics

September 1, 2009

An Archives of Internal Medicine study reported that older diabetes patients who started antipsychotic drug therapy had higher overall likelihoods of hyperglycemia.

Tumor necrosis factor blockers increase cancer risk in children

September 1, 2009

Tumor necrosis factor blockers can increase risk of lymphoma and other malignancies in pediatric patients, leading the FDA to issue a Boxed Warning mandate for these agents.

Psychiatric warning added to labels of leukotriene inhibitors used for asthma

August 1, 2009

The FDA has requested that manufacturers of asthma and rhinitis drugs with leukotriene inhibitors as the active ingredient include a psychiatric warning of mood and behavior changes among some users.

Error Watch: Lovaza omega-3 capsule contents can dissolve foam cups

August 1, 2009

The contents of Lovaza omega-3 capsules can pit or dissolve Styrofoam cups; they are now listed on the ISMP's "do not crush" list.

ADHD stimulants may be linked to childhood, adolescent cardiac deaths

August 1, 2009

The American Journal of Psychiatry has published a study documenting an association between use of stimulants for ADHD and sudden childhood deaths.

Proton-pump inhibitors increase vulnerability to pneumonia

July 1, 2009

Proton-pump inhibitors used for acid reflux have been associated with a 30% increase in risk of contracting pneumonia, according to a recent study.

Thiazolidinediones Actos and Avandia increase risk of bone fracture

July 1, 2009

The use of thiazolidinediones Actos or Avandia for treating type 2 diabetes raises the risk of bone fractures, based on the results of a large-scale, 2-year study.

FDA expands Tamiflu, Relenza indications in children due to swine flu

June 1, 2009

FDA now permits Tamiflu and Relenza use in younger children, and at different dosages in older children, in response to H1N1 flu outbreak.

Valproate linked to major birth defects

June 1, 2009

Two medical societies have issued joint guidelines warning pregnant mothers to avoid valproate (Depakote) and two other antiseizure drugs because of links to spina bifida, cleft palate, and lower child IQs.

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